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A Computational Model of Inhibition of HIV-1 by Interferon-Alpha
Type 1 interferons such as interferon-alpha (IFNα) inhibit replication of Human immunodeficiency virus (HIV-1) by upregulating the expression of genes that interfere with specific steps in the viral life cycle. This pathway thus represents a potential target for immune-based therapies that can alter...
Autores principales: | Browne, Edward P., Letham, Benjamin, Rudin, Cynthia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807028/ https://www.ncbi.nlm.nih.gov/pubmed/27010978 http://dx.doi.org/10.1371/journal.pone.0152316 |
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