GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in Erythroleukemia

GATA-1 and PU.1 are two important hematopoietic transcription factors that mutually inhibit each other in progenitor cells to guide entrance into the erythroid or myeloid lineage, respectively. PU.1 controls its own expression during myelopoiesis by binding to the distal URE enhancer, whose deletion...

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Detalles Bibliográficos
Autores principales: Burda, Pavel, Vargova, Jarmila, Curik, Nikola, Salek, Cyril, Papadopoulos, Giorgio Lucio, Strouboulis, John, Stopka, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807078/
https://www.ncbi.nlm.nih.gov/pubmed/27010793
http://dx.doi.org/10.1371/journal.pone.0152234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807078/
https://www.ncbi.nlm.nih.gov/pubmed/27010793
http://dx.doi.org/10.1371/journal.pone.0152234

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