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P-TEFb Kinase Activity Is Essential for Global Transcription, Resumption of Meiosis and Embryonic Genome Activation in Pig

Positive transcription elongation factor b (P-TEFb) is a RNA polymerase II carboxyl-terminal domain (Pol II CTD) kinase that phosphorylates Ser2 of the CTD and promotes the elongation phase of transcription. Despite the fact that P-TEFb has role in many cellular processes, the role of this kinase co...

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Detalles Bibliográficos
Autores principales: Oqani, Reza K., Lin, Tao, Lee, Jae Eun, Choi, Ki Myung, Shin, Hyun Young, Jin, Dong Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807088/
https://www.ncbi.nlm.nih.gov/pubmed/27011207
http://dx.doi.org/10.1371/journal.pone.0152254