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Microparticle-Induced Coagulation Relates to Coronary Artery Atherosclerosis in Severe Aortic Valve Stenosis

BACKGROUND: Circulating microparticles (MPs) derived from endothelial cells and blood cells bear procoagulant activity and promote thrombin generation. Thrombin exerts proinflammatory effects mediating the progression of atherosclerosis. Aortic valve stenosis may represent an atherosclerosis-like pr...

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Detalles Bibliográficos
Autores principales: Horn, Patrick, Erkilet, Gülsüm, Veulemans, Verena, Kröpil, Patric, Schurgers, Leon, Zeus, Tobias, Heiss, Christian, Kelm, Malte, Westenfeld, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807100/
https://www.ncbi.nlm.nih.gov/pubmed/27010400
http://dx.doi.org/10.1371/journal.pone.0151499