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Microparticle-Induced Coagulation Relates to Coronary Artery Atherosclerosis in Severe Aortic Valve Stenosis
BACKGROUND: Circulating microparticles (MPs) derived from endothelial cells and blood cells bear procoagulant activity and promote thrombin generation. Thrombin exerts proinflammatory effects mediating the progression of atherosclerosis. Aortic valve stenosis may represent an atherosclerosis-like pr...
Autores principales: | Horn, Patrick, Erkilet, Gülsüm, Veulemans, Verena, Kröpil, Patric, Schurgers, Leon, Zeus, Tobias, Heiss, Christian, Kelm, Malte, Westenfeld, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807100/ https://www.ncbi.nlm.nih.gov/pubmed/27010400 http://dx.doi.org/10.1371/journal.pone.0151499 |
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