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CPT-cGMP Is A New Ligand of Epithelial Sodium Channels

Epithelial sodium channels (ENaC) are localized at the apical membrane of the epithelium, and are responsible for salt and fluid reabsorption. Renal ENaC takes up salt, thereby controlling salt content in serum. Loss-of-function ENaC mutations lead to low blood pressure due to salt-wasting, while ga...

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Detalles Bibliográficos
Autores principales: Ji, Hong-Long, Nie, Hong-Guang, Chang, Yongchang, Lian, Qizhou, Liu, Shan-Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807156/
https://www.ncbi.nlm.nih.gov/pubmed/27019621
http://dx.doi.org/10.7150/ijbs.13764