Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype

Breast cancers exhibit high intertumoral heterogeneity in genetic alterations as well as histopathological and other phenotypic characteristics. The contribution of the initiating oncogenic mutation to tumor phenotype remains controversial, largely due to the technical difficulties in delivering gen...

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Detalles Bibliográficos
Autores principales: Holloway, Kimberly R., Sinha, Vidya C., Bu, Wen, Toneff, Michael, Dong, Jie, Peng, Yi, Li, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807158/
https://www.ncbi.nlm.nih.gov/pubmed/27019623
http://dx.doi.org/10.7150/ijbs.12947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807158/
https://www.ncbi.nlm.nih.gov/pubmed/27019623
http://dx.doi.org/10.7150/ijbs.12947

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