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Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies

Intrinsically disordered proteins (IDPs) are characterized by a lack of persistent structure. Since their identification more than a decade ago, many questions regarding their functional relevance and interaction mechanisms remain unanswered. Although most experiments have taken equilibrium and stru...

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Detalles Bibliográficos
Autores principales: Shammas, Sarah L., Crabtree, Michael D., Dahal, Liza, Wicky, Basile I. M., Clarke, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807256/
https://www.ncbi.nlm.nih.gov/pubmed/26851275
http://dx.doi.org/10.1074/jbc.R115.692715