Cargando…

Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis

Constitutive biosynthesis of lipid A via the Raetz pathway is essential for the viability and fitness of Gram-negative bacteria, including Chlamydia trachomatis. Although nearly all of the enzymes in the lipid A biosynthetic pathway are highly conserved across Gram-negative bacteria, the cleavage of...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Hayley E., Zhao, Jinshi, Barker, Jeffrey R., Guan, Ziqiang, Valdivia, Raphael H., Zhou, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807358/
https://www.ncbi.nlm.nih.gov/pubmed/27006461
http://dx.doi.org/10.1128/mBio.00090-16