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Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis
Constitutive biosynthesis of lipid A via the Raetz pathway is essential for the viability and fitness of Gram-negative bacteria, including Chlamydia trachomatis. Although nearly all of the enzymes in the lipid A biosynthetic pathway are highly conserved across Gram-negative bacteria, the cleavage of...
Autores principales: | Young, Hayley E., Zhao, Jinshi, Barker, Jeffrey R., Guan, Ziqiang, Valdivia, Raphael H., Zhou, Pei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807358/ https://www.ncbi.nlm.nih.gov/pubmed/27006461 http://dx.doi.org/10.1128/mBio.00090-16 |
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