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ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection

Members of the ABC-F subfamily of ATP-binding cassette proteins mediate resistance to a broad array of clinically important antibiotic classes that target the ribosome of Gram-positive pathogens. The mechanism by which these proteins act has been a subject of long-standing controversy, with two comp...

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Detalles Bibliográficos
Autores principales: Sharkey, Liam K. R., Edwards, Thomas A., O’Neill, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807367/
https://www.ncbi.nlm.nih.gov/pubmed/27006457
http://dx.doi.org/10.1128/mBio.01975-15