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The complex translocation (9;14;14) involving IGH and CEBPE genes suggests a new subgroup in B-lineage acute lymphoblastic leukemia

Many subtypes of acute lymphoblastic leukemia (ALL) are associated with specific chromosomal rearrangements. The complex translocation t(9;14;14), a variant of the translocation (14;14)(q11;q32), is a rare but recurrent chromosomal abnormality involving the immunoglobulin heavy-chain (IGH) and CCAAT...

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Detalles Bibliográficos
Autores principales: Zerrouki, Rachid, Benhassine, Traki, Bensaada, Mustapha, Lauzon, Patricia, Trabzi, Anissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807378/
https://www.ncbi.nlm.nih.gov/pubmed/27007892
http://dx.doi.org/10.1590/S1415-475738420140368