Cargando…

Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury

The low-density lipoprotein receptor (LDLR) pathway is a negative feedback system that plays important roles in the regulation of plasma and intracellular cholesterol homeostasis. To maintain a cholesterol homeostasis, LDLR expression is tightly regulated by sterol regulatory element-binding protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yang, Ma, Kun Ling, Ruan, Xiong Zhong, Liu, Bi Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807419/
https://www.ncbi.nlm.nih.gov/pubmed/27019638
http://dx.doi.org/10.7150/ijbs.14027