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Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury
The low-density lipoprotein receptor (LDLR) pathway is a negative feedback system that plays important roles in the regulation of plasma and intracellular cholesterol homeostasis. To maintain a cholesterol homeostasis, LDLR expression is tightly regulated by sterol regulatory element-binding protein...
Autores principales: | Zhang, Yang, Ma, Kun Ling, Ruan, Xiong Zhong, Liu, Bi Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807419/ https://www.ncbi.nlm.nih.gov/pubmed/27019638 http://dx.doi.org/10.7150/ijbs.14027 |
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