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Limitations of Murine Models for Assessment of Antibody-Mediated Therapies or Vaccine Candidates against Staphylococcus epidermidis Bloodstream Infection

Staphylococcus epidermidis is normally a commensal colonizer of human skin and mucus membranes, but, due to its ability to form biofilms on indwelling medical devices, it has emerged as a leading cause of nosocomial infections. Bacteremia or bloodstream infection is a frequent and costly complicatio...

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Detalles Bibliográficos
Autores principales: Cole, Leah E., Zhang, Jinrong, Kesselly, Augustus, Anosova, Natalie G., Lam, Hubert, Kleanthous, Harry, Yethon, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807487/
https://www.ncbi.nlm.nih.gov/pubmed/26857577
http://dx.doi.org/10.1128/IAI.01472-15