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Altered expression of stromal interaction molecule (STIM)-calcium release-activated calcium channel protein (ORAI) and inositol 1,4,5-trisphosphate receptors (IP(3)Rs) in cancer: will they become a new battlefield for oncotherapy?

The stromal interaction molecule (STIM)-calcium release-activated calcium channel protein (ORAI) and inositol 1,4,5-trisphosphate receptors (IP(3)Rs) play pivotal roles in the modulation of Ca(2+)-regulated pathways from gene transcription to cell apoptosis by driving calcium-dependent signaling pro...

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Detalles Bibliográficos
Autores principales: Wen, Jing, Huang, Ying-Cheng, Xiu, Huan-Huan, Shan, Zhi-Ming, Xu, Kang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807559/
https://www.ncbi.nlm.nih.gov/pubmed/27013185
http://dx.doi.org/10.1186/s40880-016-0094-2