Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies(1)

Mendelian randomization (MR) is an increasingly important tool for appraising causality in observational epidemiology. The technique exploits the principle that genotypes are not generally susceptible to reverse causation bias and confounding, reflecting their fixed nature and Mendel’s first and sec...

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Detalles Bibliográficos
Autores principales: Haycock, Philip C, Burgess, Stephen, Wade, Kaitlin H, Bowden, Jack, Relton, Caroline, Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Nutrition 2016
Materias:
Statistical Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807699/
https://www.ncbi.nlm.nih.gov/pubmed/26961927
http://dx.doi.org/10.3945/ajcn.115.118216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807699/
https://www.ncbi.nlm.nih.gov/pubmed/26961927
http://dx.doi.org/10.3945/ajcn.115.118216

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