FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells

The phase III Thai RV144 vaccine trial showed an estimated vaccine efficacy (VE) to prevent HIV-1 infection of 31.2%, which has motivated the search for immune correlates of vaccine protection. In a recent report, several single nucleotide polymorphisms (SNPs) in FCGR2C were identified to associate...

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Detalles Bibliográficos
Autores principales: Peng, Xinxia, Li, Shuying S., Gilbert, Peter B., Geraghty, Daniel E., Katze, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807760/
https://www.ncbi.nlm.nih.gov/pubmed/27015273
http://dx.doi.org/10.1371/journal.pone.0152425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807760/
https://www.ncbi.nlm.nih.gov/pubmed/27015273
http://dx.doi.org/10.1371/journal.pone.0152425

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