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Similarity in Shape Dictates Signature Intrinsic Dynamics Despite No Functional Conservation in TIM Barrel Enzymes

The conservation of the intrinsic dynamics of proteins emerges as we attempt to understand the relationship between sequence, structure and functional conservation. We characterise the conservation of such dynamics in a case where the structure is conserved but function differs greatly. The trioseph...

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Detalles Bibliográficos
Autores principales: Tiwari, Sandhya P., Reuter, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807811/
https://www.ncbi.nlm.nih.gov/pubmed/27015412
http://dx.doi.org/10.1371/journal.pcbi.1004834