An Immature Myeloid/Myeloid-Suppressor Cell Response Associated with Necrotizing Inflammation Mediates Lethal Pulmonary Tularemia

Inhalation of Francisella tularensis (Ft) causes acute and fatal pneumonia. The lung cytokine milieu favors exponential Ft replication, but the mechanisms underlying acute pathogenesis and death remain unknown. Evaluation of the sequential and systemic host immune response in pulmonary tularemia rev...

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Detalles Bibliográficos
Autores principales: Periasamy, Sivakumar, Avram, Dorina, McCabe, Amanda, MacNamara, Katherine C., Sellati, Timothy J., Harton, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807818/
https://www.ncbi.nlm.nih.gov/pubmed/27015566
http://dx.doi.org/10.1371/journal.ppat.1005517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807818/
https://www.ncbi.nlm.nih.gov/pubmed/27015566
http://dx.doi.org/10.1371/journal.ppat.1005517

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