Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

Genome-wide association studies (GWAS) have transformed our understanding of the genetics of complex traits such as autoimmune diseases, but how risk variants contribute to pathogenesis remains largely unknown. Identifying genetic variants that affect gene expression (expression quantitative trait l...

Descripción completa

Detalles Bibliográficos
Autores principales: Peters, James E., Lyons, Paul A., Lee, James C., Richard, Arianne C., Fortune, Mary D., Newcombe, Paul J., Richardson, Sylvia, Smith, Kenneth G. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807835/
https://www.ncbi.nlm.nih.gov/pubmed/27015630
http://dx.doi.org/10.1371/journal.pgen.1005908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807835/
https://www.ncbi.nlm.nih.gov/pubmed/27015630
http://dx.doi.org/10.1371/journal.pgen.1005908

Ejemplares similares