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Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum

Mutations affect individual health, population persistence, adaptation, diversification, and genome evolution. There is evidence that the mutation rate varies among genotypes, but the causes of this variation are poorly understood. Here, we link differences in genetic quality with variation in spont...

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Detalles Bibliográficos
Autores principales: Sharp, Nathaniel P., Agrawal, Aneil F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807879/
https://www.ncbi.nlm.nih.gov/pubmed/27015430
http://dx.doi.org/10.1371/journal.pbio.1002419