Enhanced dissolution and oral absorption of tacrolimus by supersaturable self-emulsifying drug delivery system

A new Soluplus (polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer)-based supersaturable self-emulsifying drug delivery system (S-SEDDS) was formulated to enhance oral absorption of tacrolimus (FK506) with minimal use of oil, surfactant, and cosurfactant. A high payload supe...

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Detalles Bibliográficos
Autores principales: Lee, Dae Ro, Ho, Myoung Jin, Jung, Hyuck Jun, Cho, Ha Ra, Park, Jun Seo, Yoon, Suk-Hyun, Choi, Yong Seok, Choi, Young Wook, Oh, Chung-Hun, Kang, Myung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807944/
https://www.ncbi.nlm.nih.gov/pubmed/27051286
http://dx.doi.org/10.2147/IJN.S102991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807944/
https://www.ncbi.nlm.nih.gov/pubmed/27051286
http://dx.doi.org/10.2147/IJN.S102991

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