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Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma

Human intrahepatic cholangiocarcinomas are one of the most difficult cancers to treat. In our study, Lovastatin, a 3-hydroxy-3-methylglutaryl-coenzyme-CoA (HMG-CoA) reductase inhibitor, demonstrated anticancer properties by inhibiting cancer cell proliferation, cell migration and cell adhesion. Lova...

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Detalles Bibliográficos
Autores principales: Yang, Sheng-Huei, Lin, Hung-Yun, Changou, Chun A, Chen, Chun-Han, Liu, Yun-Ru, Wang, Jinghan, Jiang, Xiaoqing, Luh, Frank, Yen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808004/
https://www.ncbi.nlm.nih.gov/pubmed/26517522