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Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells

Hematopoietic stem and progenitor cells (HSPCs) give rise to all of the cells that make up the hematopoietic system in the human body, making their stability and resilience especially important. Damage to these cells can severely impact cell development and has the potential to cause diseases, such...

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Detalles Bibliográficos
Autores principales: Thys, Ryan G., Lehman, Christine E., Pierce, Levi C.T., Wang, Yuh-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808301/
https://www.ncbi.nlm.nih.gov/pubmed/26163765
http://dx.doi.org/10.1016/j.mrfmmm.2015.06.011