Extract of Polygonum cuspidatum Attenuates Diabetic Retinopathy by Inhibiting the High-Mobility Group Box-1 (HMGB1) Signaling Pathway in Streptozotocin-Induced Diabetic Rats

High-mobility group box-1 (HMGB1) is a well-known pro-inflammatory cytokine. We aimed to investigate the effect of the ethanol extract of the root of P. cuspidatum (PCE) on retinal inflammation in diabetic retinopathy. PCE (100 or 350 mg/kg/day) was administered to diabetic rats for 16 weeks, and hy...

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Detalles Bibliográficos
Autores principales: Sohn, Eunjin, Kim, Junghyun, Kim, Chan-Sik, Lee, Yun Mi, Kim, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808869/
https://www.ncbi.nlm.nih.gov/pubmed/26950148
http://dx.doi.org/10.3390/nu8030140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808869/
https://www.ncbi.nlm.nih.gov/pubmed/26950148
http://dx.doi.org/10.3390/nu8030140

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