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Contrasted patterns of variation and evolutionary convergence at the antiviral OAS1 gene in old world primates

The oligoadenylate synthetase 1 (OAS1) enzyme acts as an innate sensor of viral infection and plays a major role in the defense against a wide diversity of viruses. Polymorphisms at OAS1 have been shown to correlate with differential susceptibility to several infections of great public health signif...

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Detalles Bibliográficos
Autores principales: Fish, Ian, Boissinot, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809017/
https://www.ncbi.nlm.nih.gov/pubmed/26156123
http://dx.doi.org/10.1007/s00251-015-0855-0