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Antitumor effects of cecropin B-LHRH’ on drug-resistant ovarian and endometrial cancer cells
BACKGROUND: Luteinizing hormone-releasing hormone receptor (LHRHr) represents a promising therapeutic target for treating sex hormone-dependent tumors. We coupled cecropin B, an antimicrobial peptide, to LHRH’, a form of LHRH modified at carboxyl-terminal residues 4–10, which binds to LHRHr without...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809036/ https://www.ncbi.nlm.nih.gov/pubmed/27021903 http://dx.doi.org/10.1186/s12885-016-2287-0 |