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Sustained dual release of placental growth factor-2 and bone morphogenic protein-2 from heparin-based nanocomplexes for direct osteogenesis

OBJECTIVE: To compare the direct osteogenic effect between placental growth factor-2 (PlGF-2) and bone morphogenic protein-2 (BMP-2). METHODS: Three groups of PlGF-2/BMP-2-loaded heparin–N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (HTCC) nanocomplexes were prepared: those with 0.5 μ...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Deng, Li-Zhi, Sun, Hai-Peng, Xu, Jia-Yun, Li, Yi-Ming, Xie, Xin, Zhang, Li-Ming, Deng, Fei-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809329/
https://www.ncbi.nlm.nih.gov/pubmed/27042064
http://dx.doi.org/10.2147/IJN.S100156