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High-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells

Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human adrenocortical carcinoma cells was used to evaluate the effect of 2060 chemical samples on steroidogenesis v...

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Detalles Bibliográficos
Autores principales: Karmaus, Agnes L., Toole, Colleen M., Filer, Dayne L., Lewis, Kenneth C., Martin, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809454/
https://www.ncbi.nlm.nih.gov/pubmed/26781511
http://dx.doi.org/10.1093/toxsci/kfw002