PBPK Model for Atrazine and Its Chlorotriazine Metabolites in Rat and Human

The previously-published physiologically based pharmacokinetic model for atrazine (ATZ), deisopropylatrazine (DIA), deethylatrazine (DEA), and diaminochlorotriazine (DACT), which collectively comprise the total chlorotriazines (TCT) as represented in this study, was modified to allow for scaling to...

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Detalles Bibliográficos
Autores principales: Campbell, Jerry L., Andersen, Melvin E., Hinderliter, Paul M., Yi, Kun Don, Pastoor, Timothy P., Breckenridge, Charles B., Clewell, Harvey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Pharmacokinetic Modeling of Atrazine and Metabolites
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809456/
https://www.ncbi.nlm.nih.gov/pubmed/26794140
http://dx.doi.org/10.1093/toxsci/kfw014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809456/
https://www.ncbi.nlm.nih.gov/pubmed/26794140
http://dx.doi.org/10.1093/toxsci/kfw014

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