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PBPK Model for Atrazine and Its Chlorotriazine Metabolites in Rat and Human
The previously-published physiologically based pharmacokinetic model for atrazine (ATZ), deisopropylatrazine (DIA), deethylatrazine (DEA), and diaminochlorotriazine (DACT), which collectively comprise the total chlorotriazines (TCT) as represented in this study, was modified to allow for scaling to...
Autores principales: | Campbell, Jerry L., Andersen, Melvin E., Hinderliter, Paul M., Yi, Kun Don, Pastoor, Timothy P., Breckenridge, Charles B., Clewell, Harvey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809456/ https://www.ncbi.nlm.nih.gov/pubmed/26794140 http://dx.doi.org/10.1093/toxsci/kfw014 |
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