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Alzheimer risk genes modulate the relationship between plasma apoE and cortical PiB binding

OBJECTIVE: We investigated the association between apoE protein plasma levels and brain amyloidosis and the effect of the top 10 Alzheimer disease (AD) risk genes on this association. METHODS: Our dataset consisted of 18 AD, 52 mild cognitive impairment, and 3 cognitively normal Alzheimer's Dis...

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Detalles Bibliográficos
Autores principales: Lazaris, Andreas, Hwang, Kristy S., Goukasian, Naira, Ramirez, Leslie M., Eastman, Jennifer, Blanken, Anna E., Teng, Edmond, Gylys, Karen, Cole, Greg, Saykin, Andrew J., Shaw, Leslie M., Trojanowski, John Q., Jagust, William J., Weiner, Michael W., Apostolova, Liana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809461/
https://www.ncbi.nlm.nih.gov/pubmed/27066559
http://dx.doi.org/10.1212/NXG.0000000000000022