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Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells

Artonin E is a prenylated flavonoid isolated from the stem bark of Artocarpus elasticus Reinw.(Moraceae). This study aimed to investigate the apoptotic mechanisms induced by artonin E in a metastatic human ovarian cancer cell line SKOV-3 in vitro. MTT assay, clonogenic assay, acridine orange and pro...

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Detalles Bibliográficos
Autores principales: Rahman, Mashitoh Abd, Ramli, Faiqah, Karimian, Hamed, Dehghan, Firouzeh, Nordin, Noraziah, Mohd Ali, Hapipah, Mohan, Syam, Mohd Hashim, Najihah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809498/
https://www.ncbi.nlm.nih.gov/pubmed/27019365
http://dx.doi.org/10.1371/journal.pone.0151466