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Metformin Prevents Cisplatin-Induced Cognitive Impairment and Brain Damage in Mice

RATIONALE: Chemotherapy-induced cognitive impairment, also known as ‘chemobrain’, is now widely recognized as a frequent adverse side effect of cancer treatment that often persists into survivorship. There are no drugs available to prevent or treat chemotherapy-induced cognitive deficits. The aim of...

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Detalles Bibliográficos
Autores principales: Zhou, Wenjun, Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809545/
https://www.ncbi.nlm.nih.gov/pubmed/27018597
http://dx.doi.org/10.1371/journal.pone.0151890