The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases

Redox and proteotoxic stress contributes to age-dependent accumulation of dysfunctional mitochondria and protein aggregates, and is associated with neurodegeneration. The free radical theory of aging inspired many studies using reactive species scavengers such as alpha-tocopherol, ascorbate and coen...

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Detalles Bibliográficos
Autores principales: Redmann, Matthew, Darley-Usmar, Victor, Zhang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809607/
https://www.ncbi.nlm.nih.gov/pubmed/27114848
http://dx.doi.org/10.14336/AD.2015.0820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809607/
https://www.ncbi.nlm.nih.gov/pubmed/27114848
http://dx.doi.org/10.14336/AD.2015.0820

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