CPEB1 Mediates Epithelial-to-Mesenchyme Transition and Breast Cancer Metastasis

In mouse mammary epithelial cells, CPEB1 mediates the apical localization of ZO-1 mRNA, which encodes a critical tight junction component. In mice lacking CPEB1 and in cultured cells from which CPEB has been depleted, randomly distributed ZO-1 mRNA leads to the loss of cell polarity. We have investi...

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Detalles Bibliográficos
Autores principales: Nagaoka, Kentaro, Fujii, Kazuki, Zhang, Haolin, Usuda, Kento, Watanabe, Gen, Ivshina, Maria, Richter, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809797/
https://www.ncbi.nlm.nih.gov/pubmed/26411364
http://dx.doi.org/10.1038/onc.2015.350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809797/
https://www.ncbi.nlm.nih.gov/pubmed/26411364
http://dx.doi.org/10.1038/onc.2015.350

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