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CPEB1 Mediates Epithelial-to-Mesenchyme Transition and Breast Cancer Metastasis

In mouse mammary epithelial cells, CPEB1 mediates the apical localization of ZO-1 mRNA, which encodes a critical tight junction component. In mice lacking CPEB1 and in cultured cells from which CPEB has been depleted, randomly distributed ZO-1 mRNA leads to the loss of cell polarity. We have investi...

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Detalles Bibliográficos
Autores principales:	Nagaoka, Kentaro, Fujii, Kazuki, Zhang, Haolin, Usuda, Kento, Watanabe, Gen, Ivshina, Maria, Richter, Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809797/ https://www.ncbi.nlm.nih.gov/pubmed/26411364 http://dx.doi.org/10.1038/onc.2015.350

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