Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism

Brain metastases (BM) are a devastating consequence of breast cancer. BM occur more frequently in patients with estrogen receptor-negative (ER−) breast cancer subtypes; HER2 overexpressing (HER2+) tumors and triple-negative (TN) (ER−, progesterone receptor-negative (PR−) and normal HER2) tumors. You...

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Detalles Bibliográficos
Autores principales: Sartorius, Carol A., Hanna, Colton T., Gril, Brunilde, Cruz, Hazel, Serkova, Natalie J., Huber, Kendra M., Kabos, Peter, Schedin, Troy B., Borges, Virginia F., Steeg, Patricia S., Cittelly, Diana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809801/
https://www.ncbi.nlm.nih.gov/pubmed/26411365
http://dx.doi.org/10.1038/onc.2015.353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809801/
https://www.ncbi.nlm.nih.gov/pubmed/26411365
http://dx.doi.org/10.1038/onc.2015.353

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