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Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism

Brain metastases (BM) are a devastating consequence of breast cancer. BM occur more frequently in patients with estrogen receptor-negative (ER−) breast cancer subtypes; HER2 overexpressing (HER2+) tumors and triple-negative (TN) (ER−, progesterone receptor-negative (PR−) and normal HER2) tumors. You...

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Detalles Bibliográficos
Autores principales:	Sartorius, Carol A., Hanna, Colton T., Gril, Brunilde, Cruz, Hazel, Serkova, Natalie J., Huber, Kendra M., Kabos, Peter, Schedin, Troy B., Borges, Virginia F., Steeg, Patricia S., Cittelly, Diana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809801/ https://www.ncbi.nlm.nih.gov/pubmed/26411365 http://dx.doi.org/10.1038/onc.2015.353

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