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A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
Within tumors, some areas are less oxygenated than others. Since their home ground is under chronic hypoxia, tumor cells adapt to this condition by activating aerobic glycolysis; however, this hypoxic environment is very harsh for incoming immune cells. Deprivation of oxygen limits availability of e...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809887/ https://www.ncbi.nlm.nih.gov/pubmed/27066002 http://dx.doi.org/10.3389/fimmu.2016.00109 |