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Microarray Analysis of Differentially-Expressed Genes Encoding CYP450 and Phase II Drug Metabolizing Enzymes in Psoriasis and Melanoma

Cytochrome P450 drug metabolizing enzymes are implicated in personalized medicine for two main reasons. First, inter-individual variability in CYP3A4 expression is a confounding factor during cancer treatment. Second, inhibition or induction of CYP3A4 can trigger adverse drug–drug interactions. Howe...

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Detalles Bibliográficos
Autores principales: Sumantran, Venil N., Mishra, Pratik, Bera, Rakesh, Sudhakar, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810080/
https://www.ncbi.nlm.nih.gov/pubmed/26901218
http://dx.doi.org/10.3390/pharmaceutics8010004