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Activation of α7 Nicotinic Acetylcholine Receptor Decreases On-site Mortality in Crush Syndrome through Insulin Signaling-Na/K-ATPase Pathway

On-site mortality in crush syndrome remains high due to lack of effective drugs based on definite diagnosis. Anisodamine (Ani) is widely used in China for treatment of shock, and activation of α7 nicotinic acetylcholine receptor (α7nAChR) mediates such antishock effect. The present work was designed...

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Detalles Bibliográficos
Autores principales: Fan, Bo-Shi, Zhang, En-Hui, Wu, Miao, Guo, Jin-Min, Su, Ding-Feng, Liu, Xia, Yu, Jian-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810156/
https://www.ncbi.nlm.nih.gov/pubmed/27065867
http://dx.doi.org/10.3389/fphar.2016.00079