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Activation of α7 Nicotinic Acetylcholine Receptor Decreases On-site Mortality in Crush Syndrome through Insulin Signaling-Na/K-ATPase Pathway
On-site mortality in crush syndrome remains high due to lack of effective drugs based on definite diagnosis. Anisodamine (Ani) is widely used in China for treatment of shock, and activation of α7 nicotinic acetylcholine receptor (α7nAChR) mediates such antishock effect. The present work was designed...
Autores principales: | Fan, Bo-Shi, Zhang, En-Hui, Wu, Miao, Guo, Jin-Min, Su, Ding-Feng, Liu, Xia, Yu, Jian-Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810156/ https://www.ncbi.nlm.nih.gov/pubmed/27065867 http://dx.doi.org/10.3389/fphar.2016.00079 |
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