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Shiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic Applications

Shiga toxins (Stxs) produced by Shiga toxin-producing bacteria Shigella dysenteriae serotype 1 and select serotypes of Escherichia coli are primary virulence factors in the pathogenesis of hemorrhagic colitis progressing to potentially fatal systemic complications, such as hemolytic uremic syndrome...

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Detalles Bibliográficos
Autores principales: Lee, Moo-Seung, Koo, Sunwoo, Jeong, Dae Gwin, Tesh, Vernon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810222/
https://www.ncbi.nlm.nih.gov/pubmed/26999205
http://dx.doi.org/10.3390/toxins8030077