Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium

Dynamic changes in membrane protein composition of the primary cilium are central to development and homeostasis, but we know little about mechanisms regulating membrane protein flux. Stimulation of the sonic hedgehog (Shh) pathway in vertebrates results in accumulation and activation of the effecto...

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Detalles Bibliográficos
Autores principales: Pal, Kasturi, Hwang, Sun-hee, Somatilaka, Bandarigoda, Badgandi, Hemant, Jackson, Peter K., DeFea, Kathryn, Mukhopadhyay, Saikat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810300/
https://www.ncbi.nlm.nih.gov/pubmed/27002170
http://dx.doi.org/10.1083/jcb.201506132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810300/
https://www.ncbi.nlm.nih.gov/pubmed/27002170
http://dx.doi.org/10.1083/jcb.201506132

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