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The Glucotoxicity Protecting Effect of Ezetimibe in Pancreatic Beta Cells via Inhibition of CD36

Inhibition of CD36, a fatty acid transporter, has been reported to prevent glucotoxicity and ameliorate high glucose induced beta cell dysfunction. Ezetimibe is a selective cholesterol absorption inhibitor that blocks Niemann Pick C1-like 1 protein, but may exert its effect through suppression of CD...

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Detalles Bibliográficos
Autores principales: Yoon, Ji Sung, Moon, Jun Sung, Kim, Yong-Woon, Won, Kyu Chang, Lee, Hyoung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810337/
https://www.ncbi.nlm.nih.gov/pubmed/27051238
http://dx.doi.org/10.3346/jkms.2016.31.4.547