Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus

Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B lymphoma cells. While VPA blocks viral lytic gene expression, it induces...

Descripción completa

Detalles Bibliográficos
Autores principales: Gorres, Kelly L., Daigle, Derek, Mohanram, Sudharshan, McInerney, Grace E., Lyons, Danielle E., Miller, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810481/
https://www.ncbi.nlm.nih.gov/pubmed/26933051
http://dx.doi.org/10.1128/mBio.00113-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810481/
https://www.ncbi.nlm.nih.gov/pubmed/26933051
http://dx.doi.org/10.1128/mBio.00113-16

Ejemplares similares