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Toll-Like Receptor 3/TRIF-Dependent IL-12p70 Secretion Mediated by Streptococcus pneumoniae RNA and Its Priming by Influenza A Virus Coinfection in Human Dendritic Cells

A functional immune response is crucial to prevent and limit infections with Streptococcus pneumoniae. Dendritic cells (DCs) play a central role in orchestrating the adaptive and innate immune responses by communicating with other cell types via antigen presentation and secretion of cytokines. In th...

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Detalles Bibliográficos
Autores principales: Spelmink, Laura, Sender, Vicky, Hentrich, Karina, Kuri, Thomas, Plant, Laura, Henriques-Normark, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810485/
https://www.ncbi.nlm.nih.gov/pubmed/26956584
http://dx.doi.org/10.1128/mBio.00168-16