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Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency

Human cytomegalovirus (HCMV), a betaherpesvirus, persists indefinitely in the human host through poorly understood mechanisms. The UL136 gene is carried within a genetic locus important to HCMV latency termed the UL133/8 locus, which also carries UL133, UL135, and UL138. Previously, we demonstrated...

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Detalles Bibliográficos
Autores principales: Caviness, Katie, Bughio, Farah, Crawford, Lindsey B., Streblow, Daniel N., Nelson, Jay A., Caposio, Patrizia, Goodrum, Felicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810493/
https://www.ncbi.nlm.nih.gov/pubmed/26933055
http://dx.doi.org/10.1128/mBio.01986-15